منابع مشابه
1302 Cell Immunity in Graft Rejection
Measurement of cel l -mediated cytotoxic i ty (CMC) 1 directed to cell surface antigens has been faci l i ta ted by the e laborat ion of a re la t ively simple reproducible test in which ~lCr is released from labeled target cells (1-5). Other invest igators have examined certain facets of the test (6-18) and have appl ied the technique to studies of tumor allograft systems (3-5, 16, 19, 20) and...
متن کاملAntibody-Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology.
We have established a model of sensitization in nonhuman primates and tested two immunosuppressive regimens. Animals underwent fully mismatched skin transplantation, and donor-specific antibody (DSA) response was monitored by flow cross-match. Sensitized animals subsequently underwent kidney transplantation from their skin donor. Immunosuppression included tacrolimus, mycophenolate, and methylp...
متن کاملTaking First Steps Toward Modeling Risk of Rejection in Children.
SEE PAGE 670 P ediatric cardiologists envy our colleagues who treat adults with respect to their feasibility of performing clinical trials, gathering data that results in evidence-based clinical guidelines with class I recommendations, and generating validated risk prediction models, such as the Framingham Risk Score, the Seattle Heart Failure Model, and the CHARM (Candesartan in Heart failure ...
متن کاملNumerical Modeling of Feed Through Signal Rejection in FMCW GPR
FMCW georadar feed through signal rejection is simulated. A functional model is built with the help of AWR VSS design environment including MATLAB digital processing insertion. Designed model is mostly parameterized which makes it possible to bring the model closer to reality. The process of large feed through signal rejection, including modulating, demodulating and direct coupling signal frequ...
متن کاملHumoral immunity-mediated chronic rejection in liver transplantation is associated with predominant IL-10 expression.
Chronic rejection is a major cause of graft dysfunction and retransplantation after liver allotransplantation. Recent studies have implicated humoral response in this chronic rejection reaction. However, the manner in which humoral response is activated has not been fully investigated. In the present study, we address this question using our previously established chronic allograft liver reject...
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ژورنال
عنوان ژورنال: Theoretical Biology and Medical Modelling
سال: 2012
ISSN: 1742-4682
DOI: 10.1186/1742-4682-9-18